Masterclass with prof. Martine Piccart

‘Collaborations between clinical and

laboratory scientists: understanding the challenges’

Martine Piccart will receive the KNAW Bob Pinedo Cancer Care Award 2018 during the Symposium Think BIG: advances in breast cancer treatments. In the morning she will give a Masterclass for a limited number of highly motivated PhD students in oncology. Click here for the CV of prof. Piccart

Outline of the Masterclass

Important cancer discoveries in the lab reach their full potential when they are transferred to the clinic (see the recent example of the Nobel Price for the discovery of CTLA4 and PD(L)1), but the work does not stop there: which patient truly benefits from the new treatment? What are the “resistance” mechanisms? How can they be overcome? The masterclass will outline the challenges faced by translational research teams with specific examples.

    22 November 2018
    Masterclass: 10:00 – 12:00 


    0.3 ECTS
    PhD students in Oncology
    Free of charge


    De Waver, location VUmc
Cancer Center Amsterdam
sther Ruhe


Program Symposium: ‘Think BIG : advances in breast cancer treatments

12.00-12.45    Lunch and registration – foyer Amstelzaal loc. VUmc
12.45-13.00    Introduction, Geert Kazemier, Cancer Center Amsterdam
13.00-13.35    Unconventional approaches to cancer therapy – René Bernards, NKI
13.35-14.10    The BIG picture: Molecular imagina and breast cancer – Liesbeth de Vries, UMC Groningen
14.10-14.25    Physical exercise in patients with breast cancer – Laurien Buffart, Amsterdam UMC

14.25-14.50    Break

14.50-15.05    Award ceremony by Wim van Saarloos, incl. laudatio by Bob Löwenberg, chair jury
15.05-15.50    Lessons learned after two decades of internatinal  academic  research in breast cancer
                          Keynote Lecture – Martine Piccart, 
Jules Bordet Institute, Brussels, Belgium

16.00                 Reception


ImageJ/Fiji course

ImageJ or FIJI (stands for Fiji Is Just ImageJ) is a public domain image processing and analysis program. It is freely available

The main objective of this course is to give the microscopy user a global understanding of the huge potential of the program. We will go through all functionalities of the basic package and present specific tools for use in (cell) biology. During the course we will also review concepts and principles of image processing in general, in order to set a theoretical background.

The course is split over 2 days, both featuring theoretical presentations and interactive practice examples, and is intended for all microscopy users who are interested in image processing and analysis. 

The course is split over 2 days, both featuring theoretical presentations and interactive practice examples. We will introduce the basic concepts of microscopy image analysis, such as color handling, bit depth & multi-channel images. It will cover image processing in ImageJ and an overview of the many ​ image analysis functions within this free software package. We will show you how to open images from proprietary file types (such as Leica .lif and Zeiss .czi files), how to get from raw data to a multi-panel, multi-color paper or talk figure, create multi-color images, add scale bars, work with hyperstacks, and install and use plugins and macros. You will learn how to enhance and filter images, use multichannel images and stacks, and perform basic analysis such as counting cells, segmentation and intensity analysis.

In the afternoon session of day 2, we will cover more advanced analysis, identification of cell subtypes in multichannel images, colocalisation and how to write macros.

Date: Friday November 30 & December 6, 2018
Location: NKI-AvL
Target audience: This course is intended for OOA microscopy users who are interested in image processing and analysis. For practical reasons, places will be limited to 18 participants
ECTS: 0.3
Requirement: please bring your own laptop computer
Organization: NKI-AvL BioImaging Facility: Lenny Brocks, Bram van den Broek, Marolijn Mertz, Amalie
Registration: Click here to register
Registration deadline: November 9, 2018

Radiation Oncology

Radiation Oncology

Biological, Physical and Clinical Aspects

The course provides an overview of (1) radiobiological and physical principles of radiation oncology (2) technical innovation in precision radiotherapy (3) the route of the radiotherapy patient – via diagnosis, imaging and treatment planning – to therapy.

Topics that will be addressed: effects of irradiation on the DNA and cellular level; radiation response of tumours and normal tissues; physics of modern conformal radiotherapy; imaging; treatment planning; fractionation and hypofractionation; particle irradiation; image-guided radiotherapy; brachytherapy; radiotherapy in combination with chemotherapy, targeted agents, hyperthermia and immunotherapy; treatment of breast cancer, lung cancer, gynaecological and head & neck tumours; quality of life and late effects. New and exciting developments in radiation oncology will be addressed.

The course encompasses three practical trainings: (1) the radiobiology laboratory (2) computer-based target volume delineation (3) patient treatment simulation on a linear accelerator. In addition, three PhD students will be invited to give an overview about their research project.

Date and time:
Target audience


March 25 – 29 2019,  9:00 – 17:00h
OOA PhD students, researchers and trainees in oncology with biological, clinical or physics background, having particular interest in the principles and therapeutic effects of radiation.
Peter Sminia, Jan-Jakob Sonke, Lukas Stalpers

Free of charge (coffee/tea and drinks on friday included)